SCHEMBL6225973

SCHEMBL6225973

CCCCN(Cc1cccs1)C(=O)O[C@H]1CN2CCC1CC2.O=C(O[C@H]1CN2CCC1CC2)N(Cc1cccs1)Cc1cccs1

nearest known ligand 0.98

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 20/20 0.98
CHRM2 P08172 19/20 0.98
CHRM1 P11229 19/20 0.98
CHRM4 P08173 2/20 0.44
CHRM5 P08912 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2829622 0.99 CHRM3 (1.00) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL2829257 0.91 CHRM3 (1.00) CHRM3CHRM2CHRM1
SCHEMBL2835758 0.82 CHRM3 (0.82) CHRM3CHRM2CHRM1
SCHEMBL14543540 0.78 CHRM2 (0.64) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL2830935 0.78 CHRM3 (0.65) CHRM3CHRM2CHRM1
SCHEMBL2831291 0.78 CHRM2 (1.00) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL2829321 0.78 CHRM3 (0.74) CHRM3CHRM2CHRM1
SCHEMBL2830631 0.77 CHRM3 (0.76) CHRM3CHRM2CHRM1
SCHEMBL2832235 0.76 CHRM2 (1.00) CHRM3CHRM2CHRM1CHRM4CHRM5
SCHEMBL6988791 0.76 CHRM2 (0.68) CHRM3CHRM2CHRM1CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1515968-A2 QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Almirall Prodesfarma AG (CH) 2005-03-23 EP disclosed
WO-2004000840-A2 QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME ALMIRALL PRODESFARMA AG (CH) 2003-12-31 WO disclosed