SCHEMBL622606

SCHEMBL622606

CC(C)(C)OC(=O)c1ccc(NC(=O)C(OC2CCCCC2)c2ccc(S(=O)(=O)C3CC3)cc2)nc1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10140457 0.93 GCK (0.50) GCK
SCHEMBL11997732 0.92 GCK (0.57) GCK
SCHEMBL625032 0.90 GCK (0.52) GCK
SCHEMBL623294 0.87 GCK (0.68) GCK
SCHEMBL623567 0.86 GCK (0.51) GCK
SCHEMBL623569 0.84 GCK (0.49) GCK
SCHEMBL624177 0.83 GCK (0.63) GCK
SCHEMBL11971750 0.83 GCK (0.78) GCK
SCHEMBL622602 0.81 GCK (0.50) GCK
SCHEMBL11997741 0.81 GCK (0.50) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO claimed
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO disclosed