Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | FABP4 | P15090 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | STAT3 | P40763 | 13/20 | 0.72 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Andrographolide SCHEMBL14029461 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL19704806 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL12777642 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL15263160 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL12206780 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL24806666 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL12750463 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL3668454 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL20828610 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 | |
| Andrographolide SCHEMBL62263 | 1.00 | NR1H4 (1.00) | NR1H4TP53CYP3A4FABP4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15179 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121378801-B | Photo-crosslinking double-network hydrogel for promoting skin wound healing and preparation method thereof | Shandong second people's Hospital (Shandong ear nose throat hospital, Shandong ear nose throat Research Institute) (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-120796287-B | Method for improving content of andrographolide based on methyl jasmonate and ApMYC-ApHSFB b module | 广州中医药大学(广州中医药研究院) | 2026-05-15 | — | — | CN | claimed |
| CN-122005630-A | Extraction method of Cordyceps pseudoblack and medicinal application of extract thereof | 山西大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260116861-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-04-30 | — | — | US | claimed |
| US-12599677-B2 | Targeted PH sensitive liposomes | NORTHWESTERN UNIVERSITY (US) | 2026-04-14 | — | — | US | claimed |
| EP-4717315-A2 | IMPROVED AQUACULTURE FEED ADDITIVE | HP Ingredients Corp. (US) | 2026-04-01 | — | — | EP | claimed |
| US-12589088-B2 | Compositions and methods for treating cancer with andrographolide and melatonin combination therapy | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2026-03-31 | — | — | US | claimed |
| CN-121583384-A | Nucleic acid-small molecule non-covalent complex and preparation method and application thereof | 上海中医药大学 | 2026-02-27 | — | — | CN | claimed |
| US-20260041660-A1 | Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms | CHANG RICHARD L (US) | 2026-02-12 | — | — | US | claimed |
| EP-4103213-B1 | IMPROVED AQUACULTURE FEED ADDITIVE | HP INGREDIENTS CORP (US) | 2026-02-11 | — | — | EP | claimed |
| CN-1266699-A | Anti-infectious antipyretic and antalgic medicine | ZHANG WENYING (CN) | 2000-09-20 | — | — | CN | claimed |
| CN-1239657-A | Antisticking particle and powder containing sodium hyaluronate and their preparation process | LING PEIXUE (CN) | 1999-12-29 | — | — | CN | claimed |
| CN-1046089-C | Antithyroid cream for external application | CHEN LING (CN) | 1999-11-03 | — | — | CN | claimed |
| EP-0890360-A1 | A polyherbal pharmaceutical composition useful in the treatment of conditions associated with hepatitis E and hepatitis B virus infections | Dabur Research Foundation (IN) | 1999-01-13 | — | — | EP | claimed |
| US-5833994-A | TREATMENT OF HIV INFECTIONS, AIDS | PARACELSIAN, INC. (US) | 1998-11-10 | — | — | US | claimed |
| WO-1998030213-A2 | USE OF THE AH RECEPTOR AND AH RECEPTOR LIGANDS TO TREAT OR PREVENT THE CYTOPATHICITY OF VIRAL INFECTION | PARACELSIAN, INC. (US) | 1998-07-16 | — | — | WO | claimed |
| CN-1153652-A | Prepn process of antiphlogistic medicine invigorating gallbladder | FENG TIANJIONG (CN) | 1997-07-09 | — | — | CN | claimed |
| CN-1089502-A | A kind of Chinese and western drugs compound recipe novel formulation | SHENYANG PHARMACY COLLEGE (CN) | 1994-07-20 | — | — | CN | claimed |
| CN-1085079-A | Antithyroid cream for external application | CHEN LING (CN) | 1994-04-13 | — | — | CN | claimed |
| CN-1073863-A | The manufacture method of tablets for reducing enayme and replenishing liver | DENG ZHONGYUAN (CN) | 1993-07-07 | — | — | CN | claimed |