Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334652 | 0.89 | CA1 (0.39) | NPC1CA1CA2CA9CA5A | |
| SCHEMBL9138762 | 0.87 | NPC1 (0.43) | NPC1CA1CA2CA9CA5A | |
| SCHEMBL6228820 | 0.84 | CA1 (0.59) | NPC1CA1CA2CA9CA5A | |
| SCHEMBL10762540 | 0.82 | CA1 (0.37) | NPC1CA1CA2CA9CA5A | |
| SCHEMBL9139455 | 0.81 | CA12 (0.40) | NPC1CA1CA2CA9PDK2 | |
| SCHEMBL9023824 | 0.81 | CA12 (0.40) | NPC1CA1CA2CA9CA12 | |
| SCHEMBL30806173 | 0.80 | TSHR (0.56) | NPC1CA1CA2CA9CA5A | |
| SCHEMBL9188413 | 0.80 | TSHR (0.56) | NPC1CA1CA2CA9CA5A | |
| SCHEMBL7029099 | 0.80 | NPC1 (0.44) | NPC1CA1CA2CA9PDK2 | |
| SCHEMBL7023390 | 0.79 | NPC1 (0.43) | NPC1CA1CA2CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046626-B1 | SUBSTITUTED BENZENESULFONYL ISOCYANATES AND PREPARATION THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-08 | — | — | EP | claimed |
| EP-0046626-A2 | Substituted benzenesulfonyl isocyanates and preparation thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-03 | — | — | EP | claimed |
| US-4238621-A | CARBONYLBENZENESULFONYL ISOCYANATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-12-09 | — | — | US | claimed |
| EP-1113009-B1 | A process for the manufacture of the salts of sulfonylaminocarbonyl triazolinones | BAYER AG (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-0683157-B1 | Sulfonylaminocarbonyltriazolinones as herbicides | BAYER CROPSCIENCE AG (DE) | 2004-05-26 | — | — | EP | disclosed |
| EP-1113009-A1 | A process for the manufacture of the salts of sulfonylaminocarbonyl triazolinones | Bayer Corporation (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6160125-A | Process for the manufacture of sulfonylaminocarbonyl triazolinones in the presence of xylene as solvent | BAYER CORPORATION (US) | 2000-12-12 | — | — | US | disclosed |
| US-6147221-A | Process for the manufacture of sulfonylaminocarbonyl triazolinones and salts thereof | BAYER CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |
| US-6147222-A | Process for the manufacture of sulfonylaminocarbonyl triazolinones and salts thereof under pH controlled conditions | BAYER CORPORATION (US) | 2000-11-14 | — | — | US | disclosed |
| US-5869681-A | PREPARING TRIAZOLINONE INTERMEDIATE BY HEATING HYDROCARBYLOXYCARBONYL-ISOSEMICARBAZIDE TO CYCLIZE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0431291-B1 | Sulfonylaminocarbony-triazolinones having substituents attached through sulfur | BAYER AG (DE) | 1998-07-29 | — | — | EP | disclosed |
| EP-0057546-A2 | Sulfonylurea N-oxides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |
| US-4342587-A | Herbicidal pyridinsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0046626-A2 | Substituted benzenesulfonyl isocyanates and preparation thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-03 | — | — | EP | disclosed |
| US-4305884-A | 0-CARBONYLBENZENESULFONYL ISOCYANATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| EP-0034431-A2 | 2-Isocyanatosulfonylbenzoic acid esters and preparation thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0030138-A1 | Herbicidal sulfonamides, and compositions, preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |
| EP-0023140-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |
| US-4238621-A | CARBONYLBENZENESULFONYL ISOCYANATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| EP-0007687-A1 | Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-02-06 | — | — | EP | disclosed |