SCHEMBL622646

SCHEMBL622646

OC(CBr)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064612 1.00
SCHEMBL8720907 0.91 CETP (0.43)
SCHEMBL459896 0.72 CETP (0.56)
SCHEMBL6230212 0.72 CETP (0.56)
SCHEMBL17772457 0.71 TSHR (0.32)
SCHEMBL10716317 0.71 CETP (0.42)
SCHEMBL365292 0.69
SCHEMBL3284623 0.69
Calcium SCHEMBL9561192 0.69 CETP (0.53)
SCHEMBL3278137 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108178752-B Method for preparing 3,3, 3-trifluoropropene carbonate and 3,3, 3-trifluoro-1, 2-propylene glycol in co-production mode 西安近代化学研究所 2021-02-23 CN claimed
CN-108178752-A A kind of method that coproduction prepares 3,3,3- trifluoro propenes carbonic ester and tri- fluoro- 1,2- propylene glycol of 3,3,3- 西安近代化学研究所 2018-06-19 CN claimed
CN-121824364-A Preparation method of 2- ((adamantane-1-carbonyl) oxy) -3, 3-trifluoropropane-1-sulfonate triphenylsulfonium salt 成都东凯芯半导体材料有限公司 2026-04-10 CN disclosed
CN-116535422-B HPK1 inhibitor with five-membered aromatic heterocyclic piperidine/homopiperidine, and preparation method and application thereof 上海交通大学 2025-04-18 CN disclosed
WO-2025076523-A1 RAS INHIBITORS AND METHODS OF USE THEREOF KESTREL THERAPEUTICS, INC. (US) 2025-04-10 WO disclosed
US-12239643-B2 Therapeutic agent for inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases MEIJI SEIKA PHARMA CO., LTD. (JP) 2025-03-04 US disclosed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
US-12012392-B2 Sulfonamide carboxamide compounds INFLAZOME LIMITED (IE) 2024-06-18 US disclosed
US-20240158412-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF FAXIAN THERAPEUTICS, LLC 2024-05-16 US disclosed
US-20240122180-A1 FUNGICIDAL HALOMETHYL KETONES AND HYDRATES AND THEIR MIXTURES FMC CORPORATION 2024-04-18 US disclosed
WO-2024018403-A1 SUBSTITUTED IMIDAZOAMIDE COMPOUNDS, AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2024-01-25 WO disclosed
US-5994353-A ANTIARTHRITIC AGENTS; ANALGESICS; ANTIINFLAMMATORY AGENTS ZENECA LIMITED (GB) 1999-11-30 US disclosed
US-5845716-A Method and apparatus for dispensing liquid with gas THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1998-12-08 US disclosed
EP-0866064-A1 Improved process for the preparation of trifluoromethyloxirane BAYER AG (DE) 1998-09-23 EP disclosed
CN-1193963-A Aromatic compounds and pharmaceutical compositions containing them ZENECA LTD (GB) 1998-09-23 CN disclosed
EP-0835246-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ZENECA LIMITED (GB) 1998-04-15 EP disclosed
WO-1997000863-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ZENECA LIMITED (GB) 1997-01-09 WO disclosed
WO-1992009670-A1 POLYOXYALKYLENE GLYCOL REFRIGERATION LUBRICANTS HAVING A PARTIALLY FLUORINATED POLYMER BACKBONE ALLIED-SIGNAL INC. (US) 1992-06-11 WO disclosed
US-5100569-A For use with Freon\" replacements such as 134a ALLIED-SIGNAL INC. (US) 1992-03-31 US disclosed
US-4149010-A Synthesis of α-trifluoromethyl vinyl acetate POLAROID CORPORATION (US) 1979-04-10 US disclosed