SCHEMBL622648

SCHEMBL622648

O=C(O)C1CCN(c2cnc(NC(=O)C(OC3CCCCCC3)c3ccc(S(=O)(=O)C4CCOCC4)cc3)s2)CC1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623314 0.91 GCK (0.66) GCK
SCHEMBL625462 0.91 GCK (0.67) GCK
SCHEMBL185002 0.88 GCK (0.73) GCK
SCHEMBL625210 0.83 GCK (0.70) GCK
SCHEMBL3772633 0.83 GCK (0.68) GCK
SCHEMBL625197 0.82 GCK (0.71) GCK
SCHEMBL184597 0.79 GCK (0.69) GCK
SCHEMBL624685 0.79 GCK (0.68) GCK
SCHEMBL3767939 0.79 GCK (0.63) GCK
SCHEMBL11971841 0.79 GCK (1.00) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO claimed
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO disclosed