SCHEMBL622702

SCHEMBL622702

C=C(C)C(=O)OCCN(CCOC(=O)C(=C)C)c1ccc(N=Nc2sc(C#N)c(C)c2C#N)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ USP2 O75604 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ MCL1 Q07820 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10119046 1.00 MAPT (0.32) MAPTMEN1USP2RAB9AKMT2A
SCHEMBL622701 0.94 — —
SCHEMBL10119278 0.87 MAPT (0.32) MAPTMEN1USP2RAB9AKMT2A
SCHEMBL15181348 0.87 MAPT (0.35) MAPTMEN1USP2RAB9AKMT2A
SCHEMBL621626 0.85 — —
SCHEMBL10119045 0.84 MAPT (0.32) MAPTMEN1USP2RAB9AKMT2A
SCHEMBL10119280 0.83 MAPT (0.30) MAPTMEN1USP2RAB9AKMT2A
SCHEMBL15181346 0.81 MAPT (0.41) MAPTMEN1RAB9AKMT2ASMN1; SMN2
SCHEMBL23789580 0.81 MAPT (0.33) MAPTRAB9AKMT2A
SCHEMBL18210993 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 — — EP disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 — — US disclosed
US-9383621-B2 Electrophoretic fluids MERCK PATENT GMBH (DE) 2016-07-05 — — US disclosed
US-20140313567-A1 ELECTROPHORETIC FLUIDS E INK CORPORATION 2014-10-23 — — US disclosed
US-20130208344-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-08-15 — — US disclosed
EP-2601268-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2013-06-12 — — EP disclosed
WO-2013079158-A1 ELECTROPHORETIC FLUIDS MERCK PATENT GMBH (DE) 2013-06-06 — — WO disclosed
WO-2012019704-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2012-02-16 — — WO disclosed
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