Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232542 | 0.89 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6229093 | 0.87 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL497761 | 0.85 | SMN1; SMN2 (0.52) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6227557 | 0.82 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6228902 | 0.82 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6230314 | 0.81 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6234094 | 0.81 | NPSR1 (0.48) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6229476 | 0.80 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6231350 | 0.80 | PDE4B (0.48) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6227492 | 0.79 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933366-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6235739-B1 | ANTIINFLAMMATORY AGENTS; ANTIHISTAMINES; SKIN DISORDERS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0933366-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-08-04 | — | — | EP | disclosed |