SCHEMBL6229474

SCHEMBL6229474

CCCCc1ccc(C(c2ccc(CCCC)cc2)=[Zr](C2=CC=CC2)C2c3ccc(C(C)(C)C)cc3-c3cc(C(C)(C)C)ccc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.32
SIGMAR1 Q99720 2/20 0.31
MPL P40238 1/20 0.31
KCNH2 Q12809 1/20 0.30
ESRRG P62508 1/20 0.30
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL811873 0.99 PLK1 (0.32) PLK1SIGMAR1MPLKCNH2
Hydrochloric Acid SCHEMBL812739 0.91 MPL (0.32) PLK1SIGMAR1MPLKCNH2RARB
SCHEMBL6226723 0.88
Hydrochloric Acid SCHEMBL811664 0.86
Hydrochloric Acid SCHEMBL811569 0.86 RARB (0.30) PLK1RARB
SCHEMBL18240818 0.85 RARB (0.32) RARB
SCHEMBL2861724 0.84 NPC1 (0.32)
Hydrochloric Acid SCHEMBL812376 0.84 RARB (0.32) RARB
SCHEMBL4497636 0.83 TRPV1 (0.32)
Hydrochloric Acid SCHEMBL812125 0.83 NPC1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2465879-B1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same MITSUI CHEMICALS INC (JP) 2019-04-24 EP disclosed
EP-2511305-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-10-17 EP disclosed
EP-2465879-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-2465878-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-1548018-A1 CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME Mitsui Chemicals, Inc. (JP) 2005-06-29 EP disclosed