Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1194675 | 0.99 | GLA (0.51) | GLAGAAMAPTCYP2D6HSP90AA1 | |
| Bromide SCHEMBL7113514 | 0.90 | GLA (0.48) | GLACYP2D6HSP90AA1KAT6AKMT2A | |
| SCHEMBL6911054 | 0.85 | GLA (0.51) | GLAGAACYP2D6HSP90AA1KAT6A | |
| Bromide SCHEMBL1194102 | 0.85 | KAT6A (0.54) | GLAGAAKAT6AKMT2AHTT | |
| Bromide SCHEMBL1194002 | 0.84 | GLA (0.53) | GLAGAAMAPTCYP2D6HSP90AA1 | |
| SCHEMBL6230381 | 0.84 | KMT2A (0.51) | GLAGAAMAPTCYP2D6HSP90AA1 | |
| Bromide SCHEMBL1193689 | 0.83 | KMT2A (0.53) | GLAGAAMAPTCYP2D6KMT2A | |
| SCHEMBL1194164 | 0.82 | GLA (0.53) | GLAGAAMAPTCYP2D6HSP90AA1 | |
| Bromide SCHEMBL7695782 | 0.81 | GLA (0.48) | GLACYP2D6HSP90AA1KAT6AKMT2A | |
| Bromide SCHEMBL6225758 | 0.81 | GLA (0.55) | GLAGAAMAPTCYP2D6HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243581-B1 | Pyridinium compounds useful for the treatment of AGE-related diseases | TORRENT PHARMACEUTICALS LTD (IN) | 2005-07-13 | — | — | EP | claimed |