Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936028 | 0.92 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL6237332 | 0.91 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL5936097 | 0.90 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL5936021 | 0.89 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL5936150 | 0.87 | MCHR1 (0.81) | MCHR1KCNH2 | |
| SCHEMBL5936091 | 0.86 | MCHR1 (0.79) | MCHR1KCNH2 | |
| SCHEMBL5766741 | 0.86 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL5936127 | 0.85 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL5936007 | 0.84 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL5936029 | 0.83 | MCHR1 (0.85) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |