⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337440 | 1.00 | — | — | |
| SCHEMBL6231048 | 1.00 | — | — | |
| SCHEMBL1723721 | 0.84 | NPC1 (0.41) | — | |
| SCHEMBL28025732 | 0.79 | — | — | |
| SCHEMBL10520069 | 0.79 | NPC1 (0.32) | — | |
| SCHEMBL19367701 | 0.78 | NPC1 (0.63) | — | |
| SCHEMBL786360 | 0.74 | NPC1 (0.46) | — | |
| SCHEMBL11299098 | 0.74 | — | — | |
| SCHEMBL1714656 | 0.74 | NPC1 (0.46) | — | |
| SCHEMBL11299096 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114554848-A | Process for the synthesis of picolinamides | 科迪华农业科技有限责任公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-113135870-B | Method for preparing chiral alpha-aryl carbonyl compound and product | 浙江师范大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-113135870-A | Method for preparing chiral alpha-aryl carbonyl compound and product | 浙江师范大学 | 2021-07-20 | — | — | CN | disclosed |
| US-8263659-B2 | Thyroid receptor ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| US-20100298276-A1 | THYROID RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY | 2010-11-25 | — | — | US | disclosed |
| US-7557143-B2 | Thyroid receptor ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-07-07 | — | — | US | disclosed |
| US-7507820-B2 | Diazaphosphacycles | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-03-24 | — | — | US | disclosed |
| US-6900313-B2 | Chiral ionic liquids | MERCK PATENT GMBH (DE) | 2005-05-31 | — | — | US | disclosed |
| EP-1250299-B1 | CHIRAL IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2005-04-06 | — | — | EP | disclosed |
| US-20030149264-A1 | Chiral ionic liquids | SOLVENT INNOVATION GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| EP-1250299-A2 | CHIRAL IONIC LIQUIDS | Solvent Innovation GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055060-A2 | CHIRAL IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2001-08-02 | — | — | WO | disclosed |