Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4090662 | 0.99 | CHRM2 (0.58) | CHRM2CHRM1CHRM3CYP2D6CHRM4 | |
| Iodide SCHEMBL4094587 | 0.91 | CHRM2 (0.55) | CHRM2CHRM1CHRM3CYP2D6CHRM4 | |
| SCHEMBL5007267 | 0.86 | CHRM3 (0.55) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL5009368 | 0.86 | CHRM2 (0.44) | CHRM2CHRM1CHRM3L3MBTL1BCHE | |
| SCHEMBL5007152 | 0.84 | CHRM2 (0.44) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL5011098 | 0.83 | CHRM3 (0.42) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL5009300 | 0.83 | CHRM2 (0.42) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL5003306 | 0.83 | CHRM3 (0.59) | CHRM2CHRM1CHRM3 | |
| SCHEMBL2813858 | 0.83 | CHRM3 (0.59) | CHRM2CHRM1CHRM3 | |
| SCHEMBL5006856 | 0.82 | CHRM3 (0.42) | CHRM2CHRM1CHRM3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515968-A2 | QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Almirall Prodesfarma AG (CH) | 2005-03-23 | — | — | EP | claimed |
| WO-2004000840-A2 | QUINUCLIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | ALMIRALL PRODESFARMA AG (CH) | 2003-12-31 | — | — | WO | claimed |