Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411334 | 0.89 | KCNH2 (0.38) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL11576770 | 0.85 | TLR8 (0.41) | KCNH2TLR8TLR7 | |
| SCHEMBL9580901 | 0.82 | TLR8 (0.47) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL8027997 | 0.80 | KCNH2 (0.35) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL6691988 | 0.80 | TLR8 (0.40) | KCNH2TLR8TLR7 | |
| SCHEMBL6754311 | 0.77 | CYP2D6 (0.35) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| Formaldehyde SCHEMBL14735980 | 0.77 | TLR8 (0.43) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL6262182 | 0.77 | TLR8 (0.33) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL6262284 | 0.76 | KCNH2 (0.32) | KCNH2CYP2D6DRD1HTR2AADORA1 | |
| SCHEMBL15437996 | 0.76 | MEN1 (0.33) | KCNH2CYP2D6DRD1HTR2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | disclosed |