Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524697 | 0.84 | MAOB (1.00) | MAOBCA1CA2ARG2ALDH1A1 | |
| SCHEMBL155055 | 0.84 | MAOB (1.00) | MAOBCA1CA2ARG2ALDH1A1 | |
| SCHEMBL155054 | 0.84 | MAOB (1.00) | MAOBCA1CA2ARG2ALDH1A1 | |
| SCHEMBL15527347 | 0.83 | MAOB (0.48) | MAOBALDH1A1TDP1GPR52IDO1 | |
| SCHEMBL3847991 | 0.83 | MAOB (0.48) | MAOBALDH1A1TDP1GPR52IDO1 | |
| SCHEMBL28760384 | 0.79 | MAOB (0.42) | MAOBGPR52IDO1HTR2ATAAR1 | |
| SCHEMBL6667272 | 0.78 | MAOB (0.48) | MAOBCA1CA2ARG2ALDH1A1 | |
| SCHEMBL28743524 | 0.78 | IDO1 (0.44) | MAOBIDO1HTR2ATAAR1 | |
| SCHEMBL3293785 | 0.78 | MAOB (0.75) | MAOBCA1CA2ARG2ALDH1A1 | |
| SCHEMBL28348050 | 0.78 | MAOB (0.75) | MAOBCA1CA2ARG2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529030-A2 | DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID | Prestwick Pharmaceuticals, Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004016580-A2 | DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID | PRESTWICK PHARMACEUTICALS, INC. (US) | 2004-02-26 | — | — | WO | disclosed |