Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229054 | 0.94 | ESR1 (0.48) | KDM4EPOLBESR1ALDH1A1CHRM1 | |
| SCHEMBL6230637 | 0.93 | ESR1 (0.50) | KDM4EPOLBESR1TSHRTDP1 | |
| SCHEMBL6233268 | 0.92 | KDM4E (0.48) | KDM4EPOLBESR1ALDH1A1CHRM1 | |
| SCHEMBL6232355 | 0.88 | KDM4E (0.60) | KDM4EPOLBESR1ALDH1A1CHRM1 | |
| SCHEMBL6232611 | 0.84 | CA9 (0.40) | KDM4EPOLBESR1CA9MAPT | |
| SCHEMBL6230570 | 0.84 | ESR1 (0.50) | ESR1TSHRTDP1LMNACYP1A2 | |
| SCHEMBL6230817 | 0.79 | ESR1 (0.47) | KDM4EPOLBESR1ALDH1A1CHRM1 | |
| SCHEMBL6233680 | 0.79 | ESR1 (0.47) | KDM4EPOLBESR1ALDH1A1CHRM1 | |
| SCHEMBL6232641 | 0.79 | ESR1 (0.49) | KDM4EPOLBESR1ALDH1A1CHRM1 | |
| SCHEMBL6234838 | 0.79 | ESR1 (0.51) | KDM4EPOLBESR1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |