Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.61 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904363 | 0.83 | SRC (0.61) | SRCABL1BCRABL2 | |
| SCHEMBL3215872 | 0.82 | SRC (0.64) | SRCABL1BCR | |
| SCHEMBL4898769 | 0.82 | SRC (0.64) | SRCABL1BCRABL2 | |
| SCHEMBL4898775 | 0.82 | SRC (0.64) | SRCABL1BCRABL2 | |
| SCHEMBL4892693 | 0.79 | SRC (0.72) | SRCABL1BCRABL2 | |
| SCHEMBL4904360 | 0.79 | SRC (0.57) | SRCABL1BCRABL2 | |
| SCHEMBL4894140 | 0.78 | SRC (0.71) | SRCABL1BCRABL2 | |
| SCHEMBL4901962 | 0.78 | SRC (0.71) | SRCABL1BCRABL2 | |
| SCHEMBL4894068 | 0.77 | SRC (0.83) | SRCABL1ABL2 | |
| SCHEMBL4892713 | 0.77 | SRC (0.69) | SRCABL1BCRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565474-A2 | THIENO[3,2-B]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-B]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2005-08-24 | — | — | EP | claimed |
| WO-2004048386-A9 | THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-b]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS | WYETH CORP (US) | 2005-07-14 | — | — | WO | claimed |
| WO-2004048386-A2 | THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-b]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2004-06-10 | — | — | WO | claimed |