Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068881 | 0.92 | NOTUM (0.53) | DPP8DPP7DPP9HDAC3HDAC1 | |
| SCHEMBL29367172 | 0.88 | HDAC3 (0.63) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL28500343 | 0.86 | HDAC3 (0.66) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL550056 | 0.85 | HDAC3 (0.56) | DPP8DPP7DPP9HDAC3HDAC1 | |
| SCHEMBL25143330 | 0.82 | NOTUM (0.55) | DPP8DPP7DPP9HDAC3HDAC1 | |
| SCHEMBL6228768 | 0.81 | HDAC3 (0.68) | DPP8DPP7HDAC3HDAC1HDAC10 | |
| SCHEMBL29987139 | 0.79 | NOTUM (0.52) | DPP8DPP9HDAC3HDAC1HDAC10 | |
| SCHEMBL24817140 | 0.79 | NOTUM (0.52) | DPP8DPP9HDAC3HDAC1HDAC10 | |
| SCHEMBL4689799 | 0.79 | HDAC3 (0.57) | HDAC3HDAC1HDAC10HDAC11HPGD | |
| SCHEMBL28893796 | 0.77 | HDAC3 (0.52) | DPP8DPP9HDAC3HDAC1HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |