Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034666 | 0.93 | PPARG (0.36) | PPARGPPARAPTPN1PDE10A | |
| SCHEMBL6215845 | 0.93 | PTPN1 (0.41) | PPARGPPARAPTPN1MCL1 | |
| SCHEMBL6221713 | 0.93 | KDM4E (0.31) | PPARGPPARAPTPN1MCL1 | |
| SCHEMBL6215721 | 0.92 | PPARG (0.35) | PPARGPPARAPTPN1MCL1PDE10A | |
| SCHEMBL6218384 | 0.90 | PPARG (0.33) | PPARGPPARAPTPN1 | |
| SCHEMBL6036310 | 0.86 | PPARG (0.39) | PPARGPPARAMCL1 | |
| SCHEMBL1633621 | 0.85 | PPARG (0.48) | PPARGMCL1 | |
| SCHEMBL6034568 | 0.85 | PPARG (0.42) | PPARGMCL1 | |
| SCHEMBL6217340 | 0.84 | PPARG (0.38) | PPARGPTPN1PDE10A | |
| SCHEMBL6216367 | 0.83 | PTPN1 (0.33) | PPARGPPARAPTPN1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |