⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358922 | 0.83 | — | — | |
| SCHEMBL8414306 | 0.83 | — | — | |
| SCHEMBL811225 | 0.83 | — | — | |
| SCHEMBL1953731 | 0.83 | — | — | |
| SCHEMBL1952217 | 0.83 | — | — | |
| Iodide SCHEMBL5573312 | 0.81 | — | — | |
| Fluoride SCHEMBL5574127 | 0.81 | — | — | |
| SCHEMBL31382606 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL5379077 | 0.81 | — | — | |
| Bromide SCHEMBL5573171 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343298-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2020-05-06 | — | — | EP | disclosed |
| CN-103210047-B | The diazene * dioxide of the substitution containing N and/or the aqueous polishing composition of N '-hydroxyls-diazene * oxide salts | 巴斯夫欧洲公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-108218784-A | A kind of preparation method of Nilutamide | 吴江信凯医药科技有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-105585505-B | Novel preparation method of anergotaine intermediate 1, 2-diamino-2-methylpropane | 辽宁本源制药有限公司 | 2017-10-31 | — | — | CN | disclosed |
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-2343299-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |
| CN-105585505-A | Novel preparation method of anergotaine intermediate 1, 2-diamino-2-methylpropane | LIAONING BENYUAN PHARMACY CO LTD | 2016-05-18 | — | — | CN | disclosed |
| CN-1742066-B | The siliceous dielectric method of polishing | CABOT MICROELECTRONICS CORP. (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-103080256-B | Aqueous polishing composition and process for chemically mechanically polishing substrates containing silicon oxide dielectric and polysilicon films | BASF SE | 2015-06-24 | — | — | CN | disclosed |
| CN-103210047-A | Aqueous polishing compositions containing N-substituted diazenium dioxides and/or N'-hydroxy-diazenium oxide salts | BASF SE | 2013-07-17 | — | — | CN | disclosed |
| CN-103080256-A | Aqueous polishing composition and process for chemically mechanically polishing substrates containing silicon oxide dielectric and polysilicon films | BASF SE | 2013-05-01 | — | — | CN | disclosed |
| CN-102149783-A | Methods and compositions for polishing silicon-containing substrates | CABOT MICROELECTRONICS CORP | 2011-08-10 | — | — | CN | disclosed |
| CN-1742066-A | Method of polishing a silicon-containing dielectric | CABOT MICROELECTRONICS CORP (US) | 2006-03-01 | — | — | CN | disclosed |
| EP-1517877-A1 | PREPARATION OF CHIRAL AMINO-NITRILES | PCBU Services, Inc. (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002924-A1 | PREPARATION OF CHIRAL AMINO-NITRILES | PCBU SERVICES, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
| CN-1049214-C | Phenylimidazolidines, process for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 2000-02-09 | — | — | CN | disclosed |
| US-5902883-A | Cyanobutylation of ammonia, alkylamines and hydrazine with 3-pentenenitrile, 4-pentenenitrile or mixtures thereof | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-05-11 | — | — | US | disclosed |
| US-4133937-A | Fibers coated with triozine polymers | TEXACO INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4125513-A | Thermoplastic compositions containing triazine polymer coated reinforcing agents | TEXACO INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4100147-A | Polymerization of aliphatic nitriles | TEXACO INC. (US) | 1978-07-11 | — | — | US | disclosed |