Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968978 | 0.91 | KMT2A (0.54) | KMT2AP2RX7IMPDH2NAMPT | |
| SCHEMBL2854760 | 0.78 | KMT2A (0.55) | KMT2AP2RX7IMPDH2P2RX3 | |
| SCHEMBL2854762 | 0.78 | KMT2A (0.55) | KMT2AP2RX7IMPDH2P2RX3 | |
| SCHEMBL10656070 | 0.72 | KMT2A (0.59) | KMT2AP2RX7IMPDH2SMN1; SMN2 | |
| SCHEMBL10656076 | 0.72 | KMT2A (0.59) | KMT2AP2RX7IMPDH2SMN1; SMN2 | |
| SCHEMBL3421930 | 0.72 | KMT2A (0.49) | KMT2ALTA4HP2RX3 | |
| SCHEMBL3421929 | 0.72 | KMT2A (0.49) | KMT2ALTA4HP2RX3 | |
| SCHEMBL11246830 | 0.72 | KMT2A (0.52) | KMT2ALTA4HP2RX3SMN1; SMN2 | |
| SCHEMBL2087129 | 0.71 | KMT2A (0.80) | KMT2AIMPDH2SMN1; SMN2 | |
| SCHEMBL2087128 | 0.71 | KMT2A (0.80) | KMT2AIMPDH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |