Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31298446 | 1.00 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL6237925 | 1.00 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL31298379 | 1.00 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL6238139 | 1.00 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL6235358 | 1.00 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL31234357 | 0.81 | PIK3CD (0.46) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL27179237 | 0.81 | PIK3CD (0.46) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL1155175 | 0.80 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL25187601 | 0.78 | DPP4 (0.39) | DPP4DPP8DPP9 | |
| SCHEMBL14655277 | 0.78 | GAA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |