Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | GFER | P55789 | 1/20 | 0.74 |
| ▸ | ESRRA | P11474 | 6/20 | 0.72 |
| ▸ | PIM1 | P11309 | 2/20 | 0.70 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.70 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.70 |
| ▸ | GSK3B | P49841 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SI | P14410 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233053 | 1.00 | MAPT (0.74) | MAPTMCL1NPSR1MEN1ALDH1A1 | |
| SCHEMBL13499571 | 0.89 | PDE4B (0.72) | MAPTMCL1NPSR1MEN1ALDH1A1 | |
| SCHEMBL1249965 | 0.84 | IGF1R (0.75) | MAPTMCL1NPSR1MEN1ALDH1A1 | |
| SCHEMBL1249963 | 0.84 | IGF1R (0.75) | MAPTMCL1NPSR1MEN1ALDH1A1 | |
| SCHEMBL31521577 | 0.83 | PDE4B (1.00) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2424658 | 0.83 | PDE4B (1.00) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2424653 | 0.83 | PDE4B (1.00) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL15421515 | 0.83 | PDE4B (1.00) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL5507653 | 0.82 | ESRRA (1.00) | MAPTMCL1NPSR1MEN1ALDH1A1 | |
| SCHEMBL8271091 | 0.82 | ESRRA (1.00) | MAPTMCL1NPSR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213287-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | disclosed |
| US-6730687-B1 | THERAPY OF METABOLIC DISEASES SUCH AS DIABETES AND HYPERLIPIDEMIA AS AGONISTS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| EP-1213287-A1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |