Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 20/20 | 0.67 |
| ▸ | EGFR | P00533 | 18/20 | 0.67 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236189 | 0.86 | EGFR (0.89) | ERBB2EGFRERBB4 | |
| SCHEMBL6239703 | 0.86 | EGFR (0.89) | ERBB2EGFRERBB4 | |
| Hydrochloric Acid SCHEMBL6232716 | 0.81 | EGFR (0.73) | ERBB2EGFRERBB4ERBB3 | |
| Hydrochloric Acid SCHEMBL6232736 | 0.81 | EGFR (0.73) | ERBB2EGFRERBB4ERBB3 | |
| SCHEMBL6240817 | 0.81 | EGFR (0.62) | ERBB2EGFRERBB4ERBB3 | |
| SCHEMBL6234723 | 0.81 | EGFR (0.62) | ERBB2EGFRERBB4ERBB3 | |
| SCHEMBL6237648 | 0.81 | EGFR (1.00) | ERBB2EGFRERBB4 | |
| SCHEMBL6236515 | 0.80 | EGFR (0.71) | ERBB2EGFR | |
| SCHEMBL6237233 | 0.80 | EGFR (0.87) | ERBB2EGFRERBB4 | |
| SCHEMBL6234965 | 0.80 | EGFR (0.90) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |