Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143793 | 0.84 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL5111220 | 0.84 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL5119243 | 0.84 | AVPR2 (0.46) | AVPR2AVPR1AOXTR | |
| SCHEMBL6191112 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1AOXTR | |
| SCHEMBL5105261 | 0.81 | AVPR2 (0.45) | AVPR2AVPR1AOXTR | |
| SCHEMBL5119149 | 0.75 | AVPR2 (0.49) | AVPR2AVPR1AKMT2AOXTR | |
| SCHEMBL5117311 | 0.73 | AVPR2 (0.43) | AVPR2AVPR1A | |
| SCHEMBL5117936 | 0.73 | AVPR2 (0.43) | AVPR2AVPR1A | |
| SCHEMBL5785129 | 0.72 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL5628972 | 0.71 | AVPR2 (0.48) | AVPR2AVPR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377585-B1 | NOVEL 10-CYCLOHEXENYL-PHENYL PYRROLOBENZODIAZEPINE-3-CARBOXAMIDES AND DERIVATIVES THEREOF; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH CORP (US) | 2005-11-09 | — | — | EP | claimed |