Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 5/20 | 0.65 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | GALR2 | O43603 | 5/20 | 0.43 |
| ▸ | BCL6 | P41182 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431447 | 0.86 | GALR1 (0.67) | GALR1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4838923 | 0.86 | GALR1 (0.67) | GALR1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4832453 | 0.86 | GALR1 (0.67) | GALR1GALR2BCL6PI4KB | |
| SCHEMBL14537237 | 0.85 | GALR1 (0.66) | GALR1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4836168 | 0.85 | GALR1 (0.66) | GALR1GALR2BCL6 | |
| SCHEMBL14417456 | 0.84 | BCL6 (0.60) | GALR1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4838567 | 0.83 | GALR1 (0.62) | GALR1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4832677 | 0.83 | GALR1 (0.62) | GALR1CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4840101 | 0.82 | GALR1 (0.61) | GALR1GALR2 | |
| SCHEMBL5029007 | 0.82 | GALR1 (0.61) | GALR1CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |