SCHEMBL6233610

SCHEMBL6233610

CC(C)(c1ccccc1)c1ccc2c(c1)-c1cc(C(C)(C)c3ccccc3)ccc1C2[Zr](C1=CC=CC1)=C1CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6225752 0.95 CNR1 (0.33) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL6230266 0.94 CNR1 (0.32) CNR1CNR2ESR1ESR2
SCHEMBL7724795 0.87
SCHEMBL7575806 0.82
SCHEMBL7735593 0.82
SCHEMBL2805323 0.81
SCHEMBL7737437 0.81
SCHEMBL6226983 0.81 KDM1A (0.32) ALDH1A1
SCHEMBL6227342 0.77
SCHEMBL7579444 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511305-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-10-17 EP disclosed
EP-2465878-A1 Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same Mitsui Chemicals, Inc. (JP) 2012-06-20 EP disclosed
EP-1548018-A1 CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME Mitsui Chemicals, Inc. (JP) 2005-06-29 EP disclosed