Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236453 | 1.00 | DPP4 (0.35) | DPP4SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL25581981 | 0.89 | STS (0.37) | DPP4SMYD2HSD17B10 | |
| SCHEMBL30218143 | 0.85 | BCHE (0.33) | DPP4SMYD2SMN1; SMN2HPGD | |
| SCHEMBL29007947 | 0.84 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15348442 | 0.81 | SMYD2 (0.36) | DPP4SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15348378 | 0.80 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30790876 | 0.79 | DPP4 (0.42) | DPP4SMYD2 | |
| SCHEMBL15348608 | 0.78 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18587736 | 0.77 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL19615511 | 0.77 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |