Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237180 | 0.84 | PPARD (0.63) | PPARDPPARAPPARGMRGPRX4FFAR1 | |
| SCHEMBL6236452 | 0.81 | PPARD (0.83) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL6233944 | 0.80 | PPARD (0.56) | PPARDPPARAPPARGMRGPRX4FFAR1 | |
| SCHEMBL6234038 | 0.76 | PPARD (0.76) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL6234073 | 0.76 | PPARD (0.75) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL6219975 | 0.74 | PPARD (0.60) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL6238213 | 0.73 | PPARD (1.00) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6236846 | 0.73 | PPARD (0.74) | PPARDPPARAPPARGFFAR1VDR | |
| SCHEMBL6109864 | 0.73 | PPARD (0.61) | PPARDPPARAPPARGFFAR1PTPN1 | |
| SCHEMBL6236889 | 0.73 | PPARD (1.00) | PPARDPPARAPPARGFFAR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189895-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2005-06-08 | — | — | EP | claimed |