Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7737451 | 0.94 | MEN1 (0.35) | MEN1KMT2ACA5ACA5BCA4 | |
| Trifluoroacetic Acid SCHEMBL28322378 | 0.87 | CA4 (0.38) | CA4CA2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL65539 | 0.87 | — | — | |
| Trifluoroacetic Acid SCHEMBL2519684 | 0.87 | CA4 (0.38) | CA4CA2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28078895 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL28839753 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL28342502 | 0.83 | CA4 (0.36) | CA4CA2 | |
| Trifluoroacetic Acid SCHEMBL358827 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL28688159 | 0.80 | CA4 (0.35) | CA4CA2 | |
| Trifluoroacetic Acid SCHEMBL28078894 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913498-B1 | Electroless plating processes | SHIPLEY CO LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6861097-B1 | Electroless plating processes | SHIPLEY COMPANY, L.L.C. (US) | 2005-03-01 | — | — | US | disclosed |
| EP-0913498-A1 | Electroless plating processes | Shipley Company LLC (US) | 1999-05-06 | — | — | EP | disclosed |