Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623399 | 0.94 | EGLN1 (0.74) | EGLN1 | |
| SCHEMBL622988 | 0.92 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL622141 | 0.90 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL623547 | 0.85 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL621905 | 0.85 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL623003 | 0.85 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL621986 | 0.85 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL10227905 | 0.82 | EGLN1 (0.88) | EGLN1 | |
| SCHEMBL622647 | 0.82 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL622171 | 0.81 | EGLN1 (1.00) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603502-A1 | 4 - AMINOQUINAZOLIN- 2 - YL - 1 - PYRRAZOLE - 4 - CARBOXYLIC ACID COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2013-06-19 | — | — | EP | claimed |
| WO-2012021830-A1 | 4 - AMINOQUINAZOLIN- 2 - YL - 1 - PYRRAZOLE - 4 - CARBOXYLIC ACID COMPOUNDS AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-02-16 | — | — | WO | claimed |