Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | RYR2 | Q92736 | 10/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229458 | 0.82 | DPP8 (0.51) | NAMPTHSP90AA1 | |
| SCHEMBL15989340 | 0.81 | ESR1 (0.53) | ESR1ESR2RYR2ABHD6CA1 | |
| SCHEMBL6231359 | 0.81 | DPP8 (0.52) | ABHD6NAMPTHSP90AA1 | |
| SCHEMBL6234012 | 0.81 | HDAC8 (0.42) | NAMPT | |
| SCHEMBL6228669 | 0.81 | DPP7 (0.43) | NAMPT | |
| SCHEMBL30685013 | 0.80 | ESR1 (0.52) | ESR1ESR2RYR2ABHD6CA1 | |
| SCHEMBL6227826 | 0.80 | NAMPT (0.47) | NAMPT | |
| SCHEMBL5068829 | 0.79 | NOTUM (0.52) | NAMPTHSP90AA1 | |
| SCHEMBL16282723 | 0.79 | ESR1 (0.60) | ESR1ESR2RYR2ABHD6CA1 | |
| SCHEMBL6232215 | 0.78 | DPP7 (0.56) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |