Phthalic Acid

Phthalic Acid

SCHEMBL6234815

CCOC(=O)c1ccccc1C(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.84
ALDH1A1 P00352 7/20 0.65
HSD17B10 Q99714 2/20 0.65
CDC25B P30305 1/20 0.58
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALOX15 P16050 1/20 0.56
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPK1 P28482 1/20 0.55
KMT2A Q03164 1/20 0.54
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
KDM4E B2RXH2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29628800 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL2697040 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL9132522 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL28274022 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10CDC25BTDP1
SCHEMBL50234 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10CDC25BTDP1
Phthalic Acid SCHEMBL9132525 1.00 TSHR (0.84) TSHRALDH1A1HSD17B10CDC25BTDP1
Water SCHEMBL27398945 0.98 TSHR (0.81) TSHRALDH1A1HSD17B10CDC25BTDP1
SCHEMBL11868454 0.98 TSHR (0.81) TSHRALDH1A1HSD17B10CDC25BTDP1
SCHEMBL5022457 0.98 TSHR (0.81) TSHRALDH1A1HSD17B10CDC25BTDP1
Water SCHEMBL27398942 0.98 TSHR (0.81) TSHRALDH1A1HSD17B10CDC25BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113233658-A Phthalate process wastewater treatment system 润泰新材料股份有限公司 2021-08-10 CN disclosed
EP-0825858-B1 TIME-DEPENDANT RELEASE CAPSULES CONTAINING OMEGA-3 POLYUNSATURATED ACIDS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE TILLOTTS PHARMA AG (CH) 2005-05-04 EP disclosed
US-5948818-A Treatment of inflammatory bowel disease using oral dosage forms of omega-3 polyunsaturated acids TILLOTTS PHARMA AG (CH) 1999-09-07 US disclosed
US-5873932-A BLENDING AN ELECTRON DONATING COMPOUND, AN ELECTRON ACCEPTING COMPOUND, A METACHROMATIC TEMPERATURE ADJUSTER, AN ELECTRON ACCEPTING, LIGHT-FASTNESS PROVIDING AGENT THE PILOT INK CO., LTD. (JP) 1999-02-23 US disclosed
US-5792795-A ADMINISTERING FISH OIL POLYUNSATURATED FATTY ACIDS(OR SALTS)IN CAPSULES HAVING NEUTRAL, DELAYED RELEASE POLYACRYLATE COATINGS TILLOTTS PHARMA AG (CH) 1998-08-11 US disclosed
EP-0825858-A1 TREATMENT OF INFLAMMATORY BOWEL DISEASE USING ORAL DOSAGE FORMS OF OMEGA-3 POLYUNSATURATED ACIDS TILLOTTS PHARMA AG (CH) 1998-03-04 EP disclosed
WO-1996036329-A1 TREATMENT OF INFLAMMATORY BOWEL DISEASE USING ORAL DOSAGE FORMS OF OMEGA-3 POLYUNSATURATED ACIDS TILLOTTS PHARMA AG (CH) 1996-11-21 WO disclosed
US-4425161-A Thermochromic materials PILOT INK COMPANY, LTD., (JP) 1984-01-10 US disclosed