SCHEMBL623522

SCHEMBL623522

COC(=O)c1ccc(Oc2cnc(NC(=O)C(OC3CCc4ccccc43)c3ccc(S(=O)(=O)C4CC4)cc3)s2)cc1C

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623679 0.90 GCK (0.71) GCK
SCHEMBL624172 0.88 GCK (0.49) GCK
SCHEMBL184942 0.85 GCK (0.88) GCK
SCHEMBL11971935 0.83 GCK (0.88) GCK
SCHEMBL622902 0.83 GCK (0.81) GCK
SCHEMBL624752 0.81 GCK (0.56) GCK
SCHEMBL625025 0.81 GCK (0.74) GCK
SCHEMBL11972210 0.80 GCK (0.87) GCK
SCHEMBL11972360 0.80 GCK (0.88) GCK
SCHEMBL185077 0.79 GCK (1.00) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO claimed