Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.55 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6236520 | 0.99 | ESR1 (0.56) | ESR1ESR2SSTR2CHEK2 | |
| SCHEMBL6238253 | 0.91 | ESR1 (0.57) | ESR1ESR2SSTR2CHEK2 | |
| Hydrochloric Acid SCHEMBL6234887 | 0.90 | ESR1 (0.56) | ESR1ESR2SSTR2CHEK2 | |
| SCHEMBL6148234 | 0.90 | ESR1 (0.69) | ESR1ESR2SSTR2CHEK2 | |
| Hydrochloric Acid SCHEMBL6111606 | 0.89 | ESR1 (0.69) | ESR1ESR2SSTR2CHEK2 | |
| SCHEMBL6234735 | 0.89 | ESR1 (0.69) | ESR1ESR2SSTR2CHEK2 | |
| Hydrochloric Acid SCHEMBL6230969 | 0.86 | ESR1 (0.61) | ESR1ESR2SSTR2CHEK2 | |
| Hydrochloric Acid SCHEMBL6005752 | 0.86 | ESR1 (0.67) | ESR1ESR2SSTR2 | |
| Hydrochloric Acid SCHEMBL6004951 | 0.85 | ESR1 (0.68) | ESR1ESR2SSTR2 | |
| SCHEMBL5706949 | 0.85 | ESR1 (0.58) | ESR1ESR2SSTR2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530470-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | ELI LILLY AND COMPANY (US) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004009086-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP | ELI LILLY AND COMPANY (US) | 2004-01-29 | — | — | WO | disclosed |