SCHEMBL6235879

SCHEMBL6235879

NCCCCCc1cccc(C(F)(F)F)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.74
HDAC1 Q13547 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
IDO1 P14902 2/20 0.53
HTR2A P28223 1/20 0.51
HTR2C P28335 1/20 0.51
HTR2B P41595 1/20 0.51
MAOB P27338 4/20 0.51
MIF P14174 1/20 0.50
MAOA P21397 1/20 0.50
ACP3 P15309 1/20 0.46
GAA P10253 1/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
DAO P14920 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2095840 1.00 TAAR1 (0.74) TAAR1HDAC1HDAC8IDO1HTR2A
SCHEMBL1419866 0.98 TAAR1 (0.77) TAAR1HDAC1HDAC8IDO1HTR2A
SCHEMBL365289 0.93 TAAR1 (0.79) TAAR1HDAC1HDAC8IDO1HTR2A
Hydrochloric Acid SCHEMBL12520854 0.91 TAAR1 (0.77) TAAR1HDAC1HDAC8IDO1HTR2A
Naphthalene SCHEMBL4612922 0.87 TAAR1 (0.70) TAAR1HDAC1HDAC8IDO1HTR2A
SCHEMBL2094734 0.86 TAAR1 (0.64) TAAR1HDAC1HDAC8IDO1HTR2A
SCHEMBL12040551 0.86 TAAR1 (0.62) TAAR1HDAC1HDAC8IDO1HTR2A
SCHEMBL40017 0.85 TAAR1 (1.00) TAAR1IDO1HTR2AHTR2CHTR2B
Iodide SCHEMBL28682768 0.84 TAAR1 (0.96) TAAR1IDO1HTR2AHTR2CHTR2B
Bromide SCHEMBL29203648 0.84 TAAR1 (0.96) TAAR1IDO1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1530562-A1 OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME Central Glass Company, Limited (JP) 2005-05-18 EP disclosed
WO-2004022521-A1 OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME CENTRAL GLASS COMPANY, LIMITED (JP) 2004-03-18 WO disclosed
EP-0083612-A1 NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS FLORK, Michel (FR) 1983-07-20 EP disclosed
WO-1983000146-A1 NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS FLORK, MICHEL 1983-01-20 WO disclosed