Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672058 | 0.94 | MAPT (0.46) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL12736182 | 0.89 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL18549015 | 0.89 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL12712067 | 0.89 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL4951449 | 0.87 | PRSS1 (0.57) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL4953031 | 0.87 | PRSS1 (0.57) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL34107 | 0.87 | PRSS1 (0.54) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL13495577 | 0.85 | MAPT (0.50) | PRSS1APPMAPTALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4956812 | 0.85 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL11700281 | 0.85 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1535899-A1 | Dyeing composition comprising at least one tertiary particular p-phenylenediamine, colouring method using same | L'OREAL (FR) | 2005-06-01 | — | — | EP | disclosed |