Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236046 | 1.00 | PPARG (0.39) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4850472 | 0.96 | PPARG (0.40) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4850483 | 0.96 | PPARG (0.40) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4845611 | 0.96 | MAPT (0.38) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4845620 | 0.96 | MAPT (0.38) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4848964 | 0.95 | PPARG (0.36) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4848970 | 0.95 | PPARG (0.36) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4850617 | 0.93 | MAPT (0.38) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4850607 | 0.93 | MAPT (0.38) | PPARGPPARAMAPTALDH1A1HPGD | |
| SCHEMBL4845278 | 0.92 | MAPT (0.43) | PPARGPPARAMAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541564-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2005-06-15 | — | — | EP | disclosed |