SCHEMBL6236364

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6262359	0.92	KDR (0.56)	KDRPTK2PTK2BIGF1RPLK1
	SCHEMBL6259622	0.90	PTK2 (0.67)	KDRPTK2PTK2BIGF1RPLK1
	SCHEMBL6260019	0.88	PTK2 (0.52)	KDRPTK2PTK2BIGF1RPLK1
	Ammonia Solution, Strong SCHEMBL6833389	0.85	PTK2 (0.58)	KDRPTK2PTK2BIGF1RPLK1
	SCHEMBL6260739	0.84	EGFR (0.49)	KDRPTK2PTK2BSYKJAK2
	SCHEMBL6210787	0.83	PTK2 (0.64)	KDRPTK2PTK2BROCK2SYK
	SCHEMBL6214284	0.83	PTK2 (0.61)	KDRPTK2PTK2BIGF1RROCK2
	SCHEMBL6210226	0.83	PTK2 (0.61)	KDRPTK2PTK2BIGF1RPAK4
	SCHEMBL6209160	0.82	AURKA (0.59)	PLK1SYKJAK3DYRK1ASTK17A
	SCHEMBL6239489	0.81	KDR (0.57)	KDRPTK2PTK2BIGF1RPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.