SCHEMBL6236475

SCHEMBL6236475

CCCCC[C@H]1C[C@@H]2C=C[C@H]1C2

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.47
ALDH1A1 P00352 4/20 0.47
ALOX5 P09917 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.35
EPHX1 P07099 1/20 0.31
EPHX2 P34913 2/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13769823 1.00 KDM4E (0.47) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL250096 1.00 KDM4E (0.47) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL3165070 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6273014 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL11073764 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6268871 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL11181796 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6260191 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL250011 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL144425 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US disclosed
EP-1155057-B1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES SUMITOMO BAKELITE CO (JP) 2005-06-22 EP disclosed
CN-1554680-A In mold addition polymerization composition of norbornene-type monomers and its crosslinking addition polymer ס�ѵ�ľ��ʽ���� 2004-12-15 CN disclosed
US-20030120006-A1 In mold addition polymerization of norbornene-type monomers using group 10 metal complexes THE B.F. GOODRICH COMPANY 2003-06-26 US disclosed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US disclosed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN disclosed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP disclosed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO disclosed