Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 20/20 | 0.67 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6236613 | 0.94 | EGFR (0.66) | EGFRERBB2ERBB4 | |
| SCHEMBL6241579 | 0.92 | EGFR (0.69) | EGFRERBB2ERBB4 | |
| SCHEMBL6238635 | 0.88 | EGFR (0.71) | EGFRERBB2ERBB4 | |
| SCHEMBL6236692 | 0.88 | EGFR (0.71) | EGFRERBB2ERBB4 | |
| SCHEMBL6238702 | 0.82 | EGFR (0.85) | EGFRERBB2ERBB4 | |
| SCHEMBL6238607 | 0.82 | EGFR (0.73) | EGFRERBB2 | |
| Trifluoroacetic Acid SCHEMBL6234145 | 0.82 | EGFR (0.67) | EGFRERBB2ERBB4 | |
| SCHEMBL6236689 | 0.81 | EGFR (0.93) | EGFRERBB2ERBB4 | |
| SCHEMBL6236687 | 0.81 | EGFR (0.93) | EGFRERBB2ERBB4 | |
| SCHEMBL6494560 | 0.81 | EGFR (0.70) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |