Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.67 |
| ▸ | CNR1 | P21554 | 11/20 | 0.45 |
| ▸ | CNR2 | P34972 | 11/20 | 0.45 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230964 | 0.89 | ESR1 (0.53) | ESR1ESR2CNR1CNR2KLF10 | |
| SCHEMBL21232297 | 0.87 | ESR1 (0.74) | ESR1ESR2KLF10CHEK1FYN | |
| SCHEMBL10910269 | 0.84 | CYP3A4 (0.50) | ESR1ESR2CNR1CNR2MAPK14 | |
| SCHEMBL10748415 | 0.84 | ESR1 (0.65) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL2857428 | 0.84 | ESR1 (0.65) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL2860135 | 0.84 | ESR1 (0.65) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL30336860 | 0.84 | ESR1 (0.65) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL22368025 | 0.83 | ESR1 (0.63) | ESR1ESR2KLF10CHEK1FYN | |
| SCHEMBL31738904 | 0.82 | ESR1 (0.67) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL6056720 | 0.82 | ESR1 (0.67) | ESR1ESR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274762-B1 | POLYCARBONATE PREPARATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-05-11 | — | — | EP | disclosed |
| EP-1274762-A1 | POLYCARBONATE PREPARATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001077204-A1 | POLYCARBONATE PREPARATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2001-10-18 | — | — | WO | disclosed |
| US-6225436-B1 | REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION | THE DOW CHEMICAL COMPANY | 2001-05-01 | — | — | US | disclosed |
| EP-0941268-A1 | POLYCARBONATES | THE DOW CHEMICAL COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022522-A1 | POLYCARBONATES | THE DOW CHEMICAL COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| US-RE35499-E | MOLDED ARTICLES SUCH AS COMPACT DISKS | THE DOW CHEMICAL COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0699702-A2 | Reaction products of carbonyl compounds and dihydric phenols | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4210741-A | Phenolphthalein-dihydroxy aromatic compound polycarbonates | THE DOW CHEMICAL COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4195156-A | ALKALI METAL SALTS OF DIHYDROXY- BENZENE MONO OR DI SULFONIC ACIDS AS COMONOMERS | THE DOW CHEMICAL COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4168368-A | STRESS RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4156769-A | Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4111910-A | POLYCARBONATES HAVING CARBAMATE TERMINAL GROUPS | THE DOW CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4100139-A | Polycarbonates incorporating epihalohydrin residues | THE DOW CHEMICAL COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4059566-A | Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds | THE DOW CHEMICAL COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
| US-4055544-A | Process for making polycarbonates using ammonia or ammonia compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4020045-A | METALLIC SULFITES | THE DOW CHEMICAL COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
| US-3992357-A | THERMOPLASTIC | THE DOW CHEMICAL COMPANY (US) | 1976-11-16 | — | — | US | disclosed |