Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.58 |
| ▸ | BCR | P11274 | 17/20 | 0.58 |
| ▸ | KIT | P10721 | 5/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.58 |
| ▸ | LYN | P07948 | 3/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | FYN | P06241 | 2/20 | 0.58 |
| ▸ | CSF1R | P07333 | 2/20 | 0.58 |
| ▸ | FGR | P09769 | 2/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | BRAF | P15056 | 2/20 | 0.58 |
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.58 |
| ▸ | ABL2 | P42684 | 2/20 | 0.58 |
| ▸ | FRK | P42685 | 2/20 | 0.58 |
| ▸ | BLK | P51451 | 2/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717079 | 0.95 | ABL1 (0.60) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL715534 | 0.89 | ABL1 (0.70) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL715741 | 0.84 | ABL1 (0.80) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL5315141 | 0.83 | ABL1 (0.51) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL5315135 | 0.81 | ABL1 (0.50) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL5508986 | 0.81 | ABL1 (0.68) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL715940 | 0.80 | ABL1 (0.85) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL5186493 | 0.80 | ABL1 (0.57) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL717184 | 0.79 | ABL1 (0.87) | ABL1BCRKITPDGFRBLYN | |
| SCHEMBL717536 | 0.79 | ABL1 (0.62) | ABL1BCRKITPDGFRBLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005115304-A2 | USE OF C-KIT INHIBITORS FOR TREATING FIBRODYSPLASIA | AB SCIENCE (FR) | 2005-12-08 | — | — | WO | disclosed |