Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241196 | 1.00 | S1PR1 (0.55) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6257363 | 1.00 | S1PR1 (0.55) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6261341 | 1.00 | S1PR1 (0.55) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6258194 | 0.99 | S1PR1 (0.53) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6241770 | 0.94 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6257966 | 0.94 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6240287 | 0.94 | S1PR1 (0.51) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL6255296 | 0.94 | S1PR1 (0.50) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL1624956 | 0.90 | S1PR1 (0.56) | S1PR1S1PR4S1PR3S1PR5MEN1 | |
| SCHEMBL12721394 | 0.90 | S1PR1 (0.56) | S1PR1S1PR4S1PR3S1PR5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014603-A1 | PHOSPHINANE COMPOUNDS WITH IMMUNOMODULATING ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |