Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236925 | 1.00 | PTPN1 (0.45) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL4439815 | 0.84 | PTPN1 (0.48) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL6230519 | 0.84 | PTPN1 (0.48) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL2276857 | 0.73 | PTPN1 (0.49) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL4379744 | 0.73 | PTPN1 (0.49) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL1531291 | 0.71 | MAPT (0.58) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL5255875 | 0.71 | MAPT (0.58) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL1531292 | 0.71 | MAPT (0.58) | PTPN1PTPRAMAPTALDH1A1POLB | |
| SCHEMBL4725164 | 0.71 | MAPT (0.48) | MAPTALDH1A1POLBKDM4ERAB9A | |
| SCHEMBL14350084 | 0.71 | MAPT (0.48) | MAPTALDH1A1POLBKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |