Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 7/20 | 0.42 |
| ▸ | GALR2 | O43603 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428131 | 0.76 | GALR1 (0.46) | GALR1GALR2CHRM5CHRM1CHRM3 | |
| SCHEMBL4841219 | 0.72 | BCL6 (0.48) | GALR1GALR2BCL6MAPT | |
| SCHEMBL6863750 | 0.71 | EHMT2 (0.46) | GALR1GALR2BCL6CDK1CDK4 | |
| SCHEMBL5550587 | 0.71 | GALR1 (0.48) | GALR1GALR2BCL6INSRAXL | |
| SCHEMBL4836074 | 0.69 | EHMT2 (0.49) | GALR1GALR2BCL6AXLCDK1 | |
| SCHEMBL4835528 | 0.69 | GALR1 (0.58) | GALR1GALR2BCL6CDK1CDK4 | |
| SCHEMBL4839396 | 0.69 | GALR1 (0.47) | GALR1GALR2BCL6CDK1CDK4 | |
| SCHEMBL4836523 | 0.68 | BCL6 (0.59) | GALR1GALR2BCL6CYP2D6CYP2C19 | |
| SCHEMBL4832326 | 0.68 | BCL6 (0.59) | GALR1GALR2BCL6CYP2D6CYP2C19 | |
| SCHEMBL4835239 | 0.68 | BCL6 (0.59) | GALR1GALR2BCL6CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |