SCHEMBL6237341

SCHEMBL6237341

OBO.c1ccc(C2CCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 8/20 0.52
SIGMAR1 Q99720 2/20 0.52
TRPA1 O75762 1/20 0.48
CYP2D6 P10635 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
ALDH1A1 P00352 1/20 0.46
APEX1 P27695 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5926988 0.93 SLC18A3 (0.55) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
SCHEMBL4362865 0.90 SLC18A3 (0.56) SLC18A3SIGMAR1CYP2D6SMN1; SMN2CYP1A2
SCHEMBL2050 0.90 SLC18A3 (0.61) SLC18A3SIGMAR1TRPA1CYP2D6CYP1A2
Hydrogen Peroxide SCHEMBL2352938 0.87 SLC18A3 (0.58) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
Bicarbonate SCHEMBL11121465 0.86 AKR1C3 (0.53) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL11586135 0.85 SLC18A3 (0.61) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL42934 0.85 SLC18A3 (0.61) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL9997756 0.85 SLC18A3 (0.61) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL2352896 0.85 SLC18A3 (0.61) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL5901852 0.85 SLC18A3 (0.61) SLC18A3SIGMAR1TRPA1CYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005019229-A1 PROCESS FOR PURIFICATION OF BORONIC ACID AND ITS DERIVATIVES BIOCON LIMITED (IN) 2005-03-03 WO disclosed