SCHEMBL623737

SCHEMBL623737

O=C(O)c1ccc(Oc2cnc(NC(=O)C(OC3CCCCC3)c3ccc([S+]([O-])C4CC4)cc3)s2)cc1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL623676 0.92 GCK (0.51) GCK
SCHEMBL622616 0.85 GCK (0.74) GCK
SCHEMBL623503 0.84 GCK (0.75) GCK
SCHEMBL624963 0.79 GCK (0.62) GCK
SCHEMBL623691 0.78 GCK (0.70) GCK
SCHEMBL184372 0.78 GCK (0.84) GCK
SCHEMBL3762121 0.77 GCK (0.70) GCK
SCHEMBL623677 0.77 GCK (0.69) GCK
SCHEMBL623588 0.77 GCK (0.71) GCK
SCHEMBL623570 0.76 GCK (0.48) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO disclosed