Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 8/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237454 | 1.00 | PREP (0.53) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12721154 | 0.77 | PREP (0.48) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13720661 | 0.77 | PREP (0.48) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23662476 | 0.74 | PSMB5 (0.46) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22439241 | 0.72 | PSMB5 (0.45) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23665670 | 0.72 | PSMB5 (0.45) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23662666 | 0.72 | PSMB5 (0.45) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23451168 | 0.70 | PREP (0.40) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19889110 | 0.70 | PREP (0.40) | PREPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21911589 | 0.70 | PREP (0.40) | PREPPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121365-B1 | ORGANOBORON DERIVATIVES AND PROCESS FOR COUPLING ORGANIC COMPOUNDS | COMMW SCIENT IND RES ORG (AU) | 2005-06-08 | — | — | EP | claimed |
| US-6713566-B1 | CATALYTIC HYDROBORATION OF OLEFINIC OR ACETYLENIC FUNCTIONA-LIZED MATERIAL UNDER MILD CONDITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-30 | — | — | US | claimed |
| US-6713566-B1 | CATALYTIC HYDROBORATION OF OLEFINIC OR ACETYLENIC FUNCTIONA-LIZED MATERIAL UNDER MILD CONDITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-30 | — | — | US | disclosed |