SCHEMBL623767

SCHEMBL623767

O=C(O)c1ccc(Oc2cnc(NC(=O)C(OC3CCC4(CCCC4)CC3)c3ccc(S(=O)(=O)N4CCCC4)cc3)s2)cc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL626691 0.83 GCK (0.59) GCK
SCHEMBL627084 0.83 GCK (0.59) GCK
SCHEMBL623571 0.81 GCK (0.65) GCK
SCHEMBL253502 0.81 GCK (0.74) GCK
SCHEMBL623503 0.81 GCK (0.75) GCK
SCHEMBL622616 0.80 GCK (0.74) GCK
SCHEMBL3766355 0.79 GCK (0.68) GCK
SCHEMBL185305 0.78 GCK (1.00) GCK
SCHEMBL184372 0.78 GCK (0.84) GCK
SCHEMBL185119 0.77 GCK (1.00) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO disclosed